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Factors of acute respiratory infection among under-five children across sub-Saharan African countries using machine
Haile Mekonnen Fenta1,2, Temesgen T Zewotir3, Saloshni Naidoo4
1Discipline of Public Health Medicine, School of Nursing and Public Health College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa. hailemekonnen@gmail.com.
Insights
Machine learning accurately predicts acute respiratory infection (ARI) symptoms in sub-Saharan African children under five. Environmental factors and spatial data are key predictors, with Random Forest as the top model.
Area of Science:
- Environmental Health
- Pediatric Health
- Machine Learning Applications
Background:
- Acute Respiratory Infections (ARIs) pose a significant global health challenge for children under five.
- Sub-Saharan Africa (sSA) faces a high burden of ARI symptoms in young children.
Purpose of the Study:
- To train and evaluate ten machine learning (ML) classification models for predicting ARI symptoms in children under five in sSA countries.
- To identify key predictors for ARI symptom diagnosis using ML.
Main Methods:
- Utilized Demographic and Health Surveys data (2012-2022) from 33 sSA countries.
- Incorporated air pollution data (PM2.5, nitrogen dioxide) from NASA.
- Employed machine learning algorithms, including Random Forest, with data split for training (80%) and testing (20%).
Main Results:
- Over 327,000 children were analyzed, with prevalence rates for ARI symptoms, severe ARI, cough, and fever reported.
- Random Forest model achieved an AUC of 0.77 and accuracy of 0.72.
- Key predictors identified include spatial location, particulate matter, land surface temperature, nitrogen dioxide, and number of cattle.
Conclusions:
- Machine learning, particularly the Random Forest algorithm, demonstrates strong performance in predicting ARI symptoms in under-five children in sSA.
- Environmental and spatial factors are crucial for understanding and predicting ARI prevalence in this demographic.
Abstract:
Symptoms of Acute Respiratory infections (ARIs) among under-five children are a global health challenge. We aimed to train and evaluate ten machine learning (ML) classification approaches in predicting symptoms of ARIs reported by mothers among children younger than 5 years in sub-Saharan African (sSA) countries. We used the most recent (2012-2022) nationally representative Demographic and Health Surveys data of 33 sSA countries. The air pollution covariates such as global annual surface particulate matter (PM 2.5) and the nitrogen dioxide available in the form of raster images were obtained from the National Aeronautics and Space Administration (NASA). The MLA was used for predicting the symptoms of ARIs among under-five children. We randomly split the dataset into two, 80% was used to train the model, and the remaining 20% was used to test the trained model. Model performance was evaluated using sensitivity, specificity, accuracy, and the area under the receiver operating characteristic curve. A total of 327,507 under-five children were included in the study. About 7.10, 4.19, 20.61, and 21.02% of children reported symptoms of ARI, Severe ARI, cough, and fever in the 2 weeks preceding the survey years respectively. The prevalence of ARI was highest in Mozambique (15.3%), Uganda (15.05%), Togo (14.27%), and Namibia (13.65%,), whereas Uganda (40.10%), Burundi (38.18%), Zimbabwe (36.95%), and Namibia (31.2%) had the highest prevalence of cough. The results of the random forest plot revealed that spatial locations (longitude, latitude), particulate matter, land surface temperature, nitrogen dioxide, and the number of cattle in the houses are the most important features in predicting the diagnosis of symptoms of ARIs among under-five children in sSA. The RF algorithm was selected as the best ML model (AUC = 0.77, Accuracy = 0.72) to predict the symptoms of ARIs among children under five. The MLA performed well in predicting the symptoms of ARIs and associated predictors among under-five children across the sSA countries. Random forest MLA was identified as the best classifier to be employed for the prediction of the symptoms of ARI among under-five children.
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