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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Maternal Cardiac Function in Pregnancies with Metabolic Disorders.

Deesha Patel1, Makrina D Savvidou1,2

  • 1Academic Department of Obstetrics and Gynaecology, Chelsea and Westminster Hospital, Department of Metabolism, Digestion and Reproduction, Imperial College London, UK.

European Cardiology
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PubMed
Summary
This summary is machine-generated.

Obesity during pregnancy impacts maternal cardiac function and risks. This review examines cardiac changes in obese pregnancies, gestational diabetes, hypertension, and post-bariatric surgery outcomes.

Keywords:
Pregnancydiabeteshypertension in pregnancymetabolic disordersobesity

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Area of Science:

  • Obstetrics and Gynecology
  • Cardiology
  • Maternal-Fetal Medicine

Background:

  • Rising global obesity rates present significant risks during pregnancy.
  • Metabolic dysfunction in pregnancy is linked to maternal and perinatal complications.
  • Cardiovascular implications of obesity are understood outside pregnancy, but cardiac function during pregnancy remains under-researched.

Purpose of the Study:

  • To review current evidence on maternal cardiac function in pregnancies complicated by obesity.
  • To explore the impact of obesity-associated conditions like gestational diabetes and hypertension on cardiac function.
  • To examine cardiac adaptations in pregnancies following bariatric surgery.

Main Methods:

  • Literature review of existing studies.
  • Analysis of maternal cardiac adaptation in normal vs. obese pregnancies.
  • Examination of cardiovascular implications in gestational diabetes, chronic hypertension, and hypertensive disorders of pregnancy.
  • Assessment of pregnancy outcomes and cardiac function post-bariatric surgery.

Main Results:

  • Obesity significantly alters maternal cardiac adaptation during pregnancy.
  • Gestational diabetes and hypertensive disorders of pregnancy exacerbate cardiovascular risks.
  • Bariatric surgery prior to pregnancy improves metabolic profiles and may positively influence pregnancy outcomes and cardiac function.

Conclusions:

  • Understanding maternal cardiac function in obesity is crucial for managing pregnancy risks.
  • Further research is needed to fully elucidate the long-term cardiovascular effects in these pregnancies.
  • Pre-pregnancy bariatric surgery shows promise in mitigating risks associated with obesity in pregnancy.