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Therapeutic Myths in Solid Organ Transplantation Infectious Diseases
Kellie J Goodlet1, Erin K McCreary2, Michael D Nailor3
1Department of Pharmacy Practice, Midwestern University, Glendale, Arizona, USA.
Open Forum Infectious Diseases
|July 10, 2024
Summary
Managing infections in solid organ transplant recipients is complex. This review addresses six common therapeutic myths in antimicrobial use for transplant patients to improve care.
Area of Science:
- Infectious Diseases
- Transplantation Medicine
- Clinical Microbiology
Background:
- Solid organ transplantation involves unique infection management challenges.
- Limited high-quality clinical trials can lead to the propagation of therapeutic "myths."
- Suboptimal or excessive antimicrobial use is a concern in this patient population.
Purpose of the Study:
- To identify and discuss six prevalent therapeutic myths in infection management for solid organ transplantation.
- To provide evidence-based recommendations for clinicians caring for transplant recipients.
- To optimize antimicrobial use and improve patient outcomes.
Main Methods:
- Literature review and expert consensus.
- Discussion of common misconceptions regarding antimicrobial therapy in solid organ transplant recipients.
- Formulation of practical recommendations for clinical practice.
Main Results:
- Identified six key therapeutic myths related to antimicrobial use in solid organ transplantation.
- Provided rationales and evidence to debunk these myths.
- Offered actionable strategies for clinicians.
Conclusions:
- Addressing therapeutic myths is crucial for optimizing antimicrobial stewardship in solid organ transplantation.
- Evidence-based recommendations can guide clinicians in providing appropriate infection management.
- Improved understanding and application of guidelines can enhance care for this high-risk population.
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