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Related Concept Videos

Ovarian Cycle01:27

Ovarian Cycle

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The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
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In Vitro Fertilization01:24

In Vitro Fertilization

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In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
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Oogenesis02:07

Oogenesis

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

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The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
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Meiosis II01:57

Meiosis II

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Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
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Infertility in Females01:28

Infertility in Females

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Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
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  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Reproductive Medicine
  9. Obstetrics And Gynaecology
  11. Pregnancy Outcomes Of Assisted Reproductive Technology (art) Cycle Complicated By Ovarian Hyperstimulation Syndrome (ohss): Case Series Study.
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Reproductive Medicine
  9. Obstetrics And Gynaecology
  11. Pregnancy Outcomes Of Assisted Reproductive Technology (art) Cycle Complicated By Ovarian Hyperstimulation Syndrome (ohss): Case Series Study.

Related Experiment Video

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

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Pregnancy Outcomes of Assisted Reproductive Technology (ART) Cycle Complicated by Ovarian Hyperstimulation Syndrome (OHSS): Case Series Study.

Samaher Alfaraj1, Ashwaq A Alharbi1, Hind J Aldabal2

  • 1Obstetrics and Gynecology, Ministry of National Guard Health Affairs (MNGHA), Riyadh, SAU.

Cureus
|July 10, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Assisted reproductive technology (ART) cycles with ovarian hyperstimulation syndrome (OHSS) show a high incidence of severe OHSS and preterm deliveries, yet many women achieve pregnancy. Further management strategies are needed.

Keywords:
assisted reproductive technologycase seriesking abdulaziz medical cityovarian hyperstimulation syndrome

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Related Experiment Videos

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

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Fertility Preservation in Patients with Severe Ovarian Dysfunction
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OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
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OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

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Area of Science:

  • Reproductive Medicine
  • Obstetrics & Gynecology

Background:

  • Ovarian hyperstimulation syndrome (OHSS) is a significant complication of assisted reproductive technology (ART).
  • OHSS presents with symptoms including ovarian enlargement, fluid accumulation (ascites), and pleural effusion.
  • It poses a potentially lethal risk to patients undergoing fertility treatments.

Purpose of the Study:

  • To investigate the impact of ART cycles complicated by OHSS on pregnancy outcomes.
  • To analyze the characteristics of infertile patients undergoing ART with OHSS.

Main Methods:

  • A case series study was conducted at King Abdulaziz Medical City, Riyadh, Saudi Arabia.
  • Data from 15 patients undergoing in vitro fertilization (IVF) or intracytoplascitc sperm injection (ICSI) between 2015-2021 were analyzed.
pregnancy outcomes
  • Descriptive statistics were used to evaluate pregnancy outcomes.

    • Main Results:

    • Anovulation was the primary cause of infertility (66.7%).
    • Severe OHSS occurred in 73.3% of cases, with all severe cases involving three embryo transfers.
    • Pregnancy was achieved in 73.3% of participants, with common preterm deliveries (33.3% between 32-37 weeks) and a balanced mode of birth (vaginal vs. cesarean).

    Conclusions:

    • ART cycles complicated by OHSS, often linked to anovulation, present challenges including severe OHSS and preterm birth.
    • Despite complications, a majority of women achieved pregnancy.
    • Improved OHSS management strategies are crucial for enhancing ART pregnancy outcomes.