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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Chronic Bowel Disorders: Introduction01:17

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
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Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
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Peptic Ulcer Disease I: Introduction01:30

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Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
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Mpox-Induced Proctitis.

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Mpox (monkeypox) can cause proctitis, an infrequent initial symptom. This case highlights gastrointestinal presentations as key for early Mpox identification and treatment during global outbreaks.

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Mpox (monkeypox), a zoonotic orthopoxvirus, presents with diverse symptoms, including atypical gastrointestinal manifestations.
  • Proctitis, an inflammation of the rectum, is an uncommon but increasingly recognized initial symptom of Mpox, particularly since the 2022 global endemic.

Observation:

  • A 27-year-old male presented with anorectal bleeding and varied cutaneous lesions.
  • Symptoms began 8 days after unprotected sexual intercourse in New York City, an endemic epicenter.
  • CT imaging revealed rectal wall thickening and lymphadenopathy, indicative of acute proctitis.

Findings:

  • This case confirms proctitis as a significant, albeit infrequent, initial presentation of Mpox.
  • The prevalence of Mpox-associated proctitis has notably increased.
  • Gastrointestinal symptoms can be the primary indicator of Mpox infection.

Implications:

  • Understanding atypical Mpox presentations like proctitis is crucial for timely diagnosis.
  • Early identification of Mpox-associated proctitis facilitates prompt treatment and public health response.
  • Recognizing these unique presentations aids in managing future Mpox endemics.