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Related Concept Videos

Trachea01:22

Trachea

1.8K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
1.8K
Tracheostomy: Procedure and Tubes01:28

Tracheostomy: Procedure and Tubes

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A tracheostomy is a surgical procedure that creates an artificial opening into the trachea, typically at the second or third cartilaginous ring level. This opening allows the insertion of a tracheostomy tube, which can replace an endotracheal tube, provide mechanical ventilation, bypass an upper airway obstruction, or remove accumulated tracheobronchial secretions.
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
507
Oxygen Delivering System III: Tracheostomy and T-piece01:23

Oxygen Delivering System III: Tracheostomy and T-piece

740
Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
740
Tracheostomy Decannulation01:21

Tracheostomy Decannulation

148
Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
148
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

488
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
488
Tracheostomy Care I: Pre-procedural Steps01:16

Tracheostomy Care I: Pre-procedural Steps

169
A tracheostomy is a surgical technique that involves making an incision in the neck to provide access to the trachea. It is frequently used in medical conditions such as airway obstruction and prolonged mechanical ventilation. Effective nursing management is crucial for the long-term success of a tracheostomy.
Required Equipment
The equipment necessary for tracheostomy care includes:
169

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Related Experiment Video

Updated: Jun 21, 2025

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
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Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Published on: April 1, 2019

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Full circumferential human tracheal replacement: a systematic review.

Briac Thierry1,2, Lousineh Arakelian2,3, Françoise Denoyelle1

  • 1Department of Paediatric Otolaryngology - Head and Neck Surgery, Hôpital Universitaire Necker - Enfants Malades, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|July 10, 2024
PubMed
Summary
This summary is machine-generated.

Full Circumferential Tracheal Replacement (FCTR) is complex, with no standard technique. Vascularization and stent use are key, but functional ciliated epithelium may not be essential for tracheal regeneration.

Keywords:
Bio-integrationFull circumferential tracheal replacementThoracic surgeryTracheal disease

More Related Videos

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

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Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation
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Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation

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Last Updated: Jun 21, 2025

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation
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Area of Science:

  • Regenerative Medicine
  • Surgical Innovation
  • Biomaterials Science

Background:

  • Full Circumferential Tracheal Replacement (FCTR) presents significant surgical challenges due to extensive tracheal resection requirements.
  • Current FCTR practices lack consensus on optimal surgical techniques and biomaterials.
  • This review addresses FCTR indications, substitute materials, surgical methods, and vascularization strategies.

Approach:

  • A systematic review following PRISMA guidelines was conducted for studies published between 2000 and 2022.
  • Identified and compared FCTR cases based on surgical indications, tracheal substitutes (allografts, aorta, autologous reconstruction, tissue-engineered trachea), and immunological characteristics.
  • Evaluated surgical techniques, vascularization methods, and outcomes, including patient follow-up and mortality.

Key Points:

  • Thirty-seven patients (including five children) underwent FCTR using four distinct techniques.
  • Vascularization of the tracheal substitute, either directly via anastomosis or indirectly with vascularized tissue, is crucial for long-term biointegration.
  • While epithelial coverage is important, fully functional ciliated epithelium was not consistently necessary for successful outcomes.

Conclusions:

  • Standardized clinical trials with routine follow-up, including biomechanical assessment and biopsies, are proposed to enable future comparisons.
  • Such trials will aid in understanding tracheal bio-integration and regeneration dynamics and mechanisms.
  • Further research is needed to establish standardized protocols for Full Circumferential Tracheal Replacement.