Related Experiment Video
Updated: Jun 21, 2025

Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
Electroconvulsive Therapy in Forensic Psychiatry: A Systematic Review
Matthias Besse1, Jakov Gather, Boris Schiffer2
1From the Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen.
Electroconvulsive therapy (ECT) may benefit patients with treatment-resistant psychosis in forensic hospitals, showing symptom improvement and reduced aggression. However, more high-quality research is needed to confirm these findings.
Area of Science:
- Forensic Psychiatry
- Clinical Psychology
- Neuroscience
Background:
- Patients in forensic hospitals often have schizophrenia and treatment-resistant psychosis, leading to longer hospital stays.
- Electroconvulsive therapy (ECT) is a potential treatment for severe, treatment-resistant psychotic disorders.
- Data on ECT use in forensic psychiatry is limited, necessitating a review of existing evidence.
Approach:
- A systematic review was conducted searching PubMed, Web of Science, and PsycINFO from 1980 onwards.
- Included were peer-reviewed articles detailing ECT treatment outcomes in forensic psychiatry patients.
- Analysis focused on case reports and series with reported treatment outcomes.
Key Points:
- The review identified 6 studies (5 case reports, 1 case series) involving 13 patients treated with ECT in forensic settings.
- Patients diagnosed with schizophrenia spectrum disorders (10) or psychotic depression (3) showed improvement.
- Eleven patients (84.6%) responded to ECT, with reduced aggression and improved functioning; 3 returned to the community.
Conclusions:
- Despite poor evidence quality and high risk of bias, ECT shows potential benefit for forensic psychiatric patients.
- Further research, including prospective, controlled observational studies and qualitative patient perspectives, is crucial.
- Systematic and higher-quality evidence is urgently needed to support ECT's role in forensic psychiatry.
More Related Videos
09:07Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
07:55The Optical Fractionator Technique to Estimate Cell Numbers in a Rat Model of Electroconvulsive Therapy
Published on: July 9, 2017
Related Concept Videos
Electroconvulsive Therapy
Psychosurgery
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...