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Updated: Jun 21, 2025

Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Surgical approaches to congenital diaphragmatic hernia
Sarah King1, Benjamin D E Carr2, George B Mychaliska1
1C.S. Mott Children's Hospital, Section of Pediatric Surgery, Department of Surgery, University of Michigan. Ann Arbor, MI, USA.
Abstract:
Surgical repair of the diaphragm is essential for survival in congenital diaphragmatic hernia (CDH). There are many considerations surrounding the operation - why the operation matters, optimal timing of repair and its relation to extracorporeal life support (ECLS) use, minimally invasive versus open approaches, and strategies for reconstruction. Surgery is both affected by, and affects, the physiology of these infants and is an important factor in determining long-term outcomes. Here we discuss the evidence and provide insight surrounding this complex decision making, technical pearls, and outcomes in repair of CDH.

