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Biomedical And Clinical Sciences
Oncology And Carcinogenesis
Predictive And Prognostic Markers
Laparoscopic Versus Open Pancreaticoduodenectomy For Ampullary Cancer: A Retrospective Study.

Home
Research Domains
Biomedical And Clinical Sciences
Oncology And Carcinogenesis
Predictive And Prognostic Markers
Laparoscopic Versus Open Pancreaticoduodenectomy For Ampullary Cancer: A Retrospective Study.

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Laparoscopic versus open pancreaticoduodenectomy for ampullary cancer: A retrospective study.

Masayoshi Sakuma¹, Atsuyuki Maeda¹, Yuichi Takayama¹

¹Department of Surgery, Ogaki Municipal Hospital, Gifu, Japan.

Asian Journal of Endoscopic Surgery

|July 10, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Laparoscopic pancreaticoduodenectomy (LPD) offers outcomes comparable to open pancreaticoduodenectomy (OPD) for ampullary carcinoma (AC). LPD is a viable standard treatment due to reduced blood loss and shorter hospital stays.

Keywords:

ampullary cancer laparoscopic surgery pancreaticoduodenectomy

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Area of Science:

Surgical Oncology
Gastroenterology
Minimally Invasive Surgery

Background:

Limited comparative studies exist for laparoscopic pancreaticoduodenectomy (LPD) versus open pancreaticoduodenectomy (OPD) in ampullary carcinoma (AC).
Evaluating short- and long-term outcomes is crucial for treatment selection.

Purpose of the Study:

To compare short- and long-term outcomes of LPD and OPD for ampullary carcinoma.
To assess the efficacy and safety of LPD as a potential standard treatment for AC.

Main Methods:

Retrospective analysis of 55 patients with AC undergoing pancreaticoduodenectomy (PD) with curative intent.
Comparison of outcomes between LPD (n=26) and OPD (n=29) groups.

Main Results:

LPD showed significantly longer operative time, but less blood loss and shorter hospital stay compared to OPD.

No significant differences in morbidity, lymph node metastasis, pathological stages, overall survival (OS), or recurrence-free survival (RFS).

3- and 5-year OS rates were comparable: LPD (63.0%/54%) vs. OPD (64.8%/61.2%).

Conclusions:

LPD demonstrates comparable short- and long-term oncological outcomes to OPD for ampullary carcinoma.
LPD is a safe and effective alternative, recommended for its benefits of reduced blood loss and shorter hospital stay.