Electrochemical oxidative thioetherification of aldehyde hydrazones with thiophenols
Meiqian Hu1, Xiaolin Yang1, Shuai Zhang1
1Guangxi Key Laboratory of Electrochemical and Magnetochemical Functional Materials, College of Chemistry and Bioengineering, Guilin University of Technology, 12 Jiangan Road, Guilin 541004, China. jianggb@glut.edu.cn.
Abstract:
An electrochemically promoted oxidative dehydrogenation cross-coupling reaction between aldehyde hydrazones and thiophenols is demonstrated for the first time, which resulted in a variety of (Z)-thioetherified products in moderate to excellent yields. This strategy can be carried out under an air atmosphere, featuring scalability and excellent stereoselectivity. In addition, the transformation efficiently produces readily recyclable disulfide as a by-product with high yields, which significantly reduces the environmental pollution caused by thioetherification.
More Related Videos
Related Concept Videos
Preparation and Reactions of Thiols
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:
Preparation of Aldehydes and Ketones from Alcohols, Alkenes, and Alkynes
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...


