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Primary central nervous system angiitis: a case report
Zahraa M M Zeer1, Yasmin N A Arda1, Hasan Abu Salim2
1Faculty of Medicine, Al-Quds University, Jerusalem.
Annals of Medicine and Surgery (2012)
|July 11, 2024
Summary
Primary central nervous system angiitis is a rare condition affecting the brain and spinal cord. Early recognition of its diverse symptoms is crucial for accurate diagnosis and to avoid misdiagnosis.
Area of Science:
- Neurology
- Immunology
- Pathology
Background:
- Primary central nervous system angiitis (PCNSA) is a rare idiopathic vasculitis affecting only the central nervous system.
- It presents with diverse clinical manifestations that can mimic other vasculopathies, complicating diagnosis.
Observation:
- A case of a 24-year-old female with non-specific neurological complaints over time is presented.
- Diagnostic challenges were encountered before a tissue biopsy confirmed PCNSA.
Findings:
- Despite increasing reports, PCNSA pathogenesis remains unclear.
- Diagnosis is challenging due to lack of universal criteria and definitive diagnostic tests (lab or imaging).
Implications:
- Awareness of PCNSA differentials is vital for clinicians to prevent misdiagnosis.
- Timely and accurate diagnosis is essential for appropriate patient management.
