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Updated: Jun 21, 2025

Flow Cytometric Analysis of Lymphocyte Infiltration in Central Nervous System during Experimental Autoimmune Encephalomyelitis

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Published on: November 17, 2020

Primary central nervous system angiitis: a case report.

Zahraa M M Zeer¹, Yasmin N A Arda¹, Hasan Abu Salim²

¹Faculty of Medicine, Al-Quds University, Jerusalem.

Annals of Medicine and Surgery (2012)

|July 11, 2024

Summary

This summary is machine-generated.

Primary central nervous system angiitis is a rare condition affecting the brain and spinal cord. Early recognition of its diverse symptoms is crucial for accurate diagnosis and to avoid misdiagnosis.

Keywords:

angiitis case report histology misdiagnosis nervous system

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Area of Science:

Neurology
Immunology
Pathology

Background:

Primary central nervous system angiitis (PCNSA) is a rare idiopathic vasculitis affecting only the central nervous system.
It presents with diverse clinical manifestations that can mimic other vasculopathies, complicating diagnosis.

Observation:

A case of a 24-year-old female with non-specific neurological complaints over time is presented.
Diagnostic challenges were encountered before a tissue biopsy confirmed PCNSA.

Findings:

Despite increasing reports, PCNSA pathogenesis remains unclear.
Diagnosis is challenging due to lack of universal criteria and definitive diagnostic tests (lab or imaging).

Implications:

Awareness of PCNSA differentials is vital for clinicians to prevent misdiagnosis.
Timely and accurate diagnosis is essential for appropriate patient management.