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Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
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Updated: May 7, 2026

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Post-Viral Longitudinally Extensive Transverse Myelitis: A Case Report.

Sangram Mangudkar1, Sindhuri Goud Nimmala1, Mahabir P Mishra1

  • 1Internal Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, IND.

Cureus
|July 11, 2024
PubMed
Summary

Dengue infection can cause rare neurological issues like longitudinally extensive transverse myelitis. This case highlights a young male

Keywords:
dengue feverinfectiousintravenous immunoglobulins (ivig)longitudinally extending transverse myelitisneurotropic virus

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Neuroimmunology

Background:

  • Dengue virus infection is a significant global health concern, primarily known for its systemic effects.
  • Neurological manifestations of dengue are uncommon but can be severe, impacting patient outcomes.
  • Longitudinally extensive transverse myelitis (LETM) is a rare but serious spinal cord inflammation.

Observation:

  • A 24-year-old male presented with fever and maculopapular rash, typical symptoms of dengue fever.
  • The patient subsequently developed acute flaccid quadriparesis and urinary retention, indicating severe neurological involvement.
  • Spinal magnetic resonance imaging (MRI) revealed extensive, ill-defined hyperintense signals in the spinal cord.

Findings:

  • The clinical presentation and MRI findings were consistent with longitudinally extensive transverse myelitis secondary to dengue infection.
  • The patient experienced significant motor and autonomic dysfunction due to the spinal cord inflammation.
  • This case underscores the potential for dengue to trigger severe neuroinflammatory conditions.

Implications:

  • Early recognition of neurological complications in dengue fever is crucial for timely intervention.
  • Prompt management with immunomodulatory therapies, such as steroids and intravenous immunoglobulins, can improve neurological recovery.
  • This case expands the spectrum of known neurological manifestations of dengue virus infection.