[Treatment of gastroparesis by primperan]

The motor action of Primperan on the stomach is discussed. This action causes a significant acceleration in gastric emptying, as a result of an increased contractile activity of the stomach and a duodeno-gastric synergy. The clinical activity of Primperan in diabetic, post-surgical and idiopathic gastroparesis has been confirmed by means of double blind s studies. The daily administration of 40 mg of Primperan, in 4 divided doses before meals and at bedtime, leads to a statistically significant improvement in the gastro-intestinal symptoms of these patients.