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Related Concept Videos

COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
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COPD: Management Using Bronchodilators and Corticosteroids01:26

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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
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Pulmonary Cycle: Exhalation01:17

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In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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Related Experiment Video

Updated: Jun 21, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
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Bronchiolitis: Increased severity in the post-COVID-19 era.

Victorine Boccard1,2, Blandine Prevost1,2, Sophie Denamur1,2

  • 1Sorbonne Université, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Trousseau, Service de Pneumologie Pédiatrique, Centre de Référence des Maladies Respiratoires Rares RespiRare, Paris, France.

Pediatric Pulmonology
|July 11, 2024
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Post-COVID, infant bronchiolitis cases show increased severity and higher Respiratory Syncytial Virus (RSV) rates. Preventive measures like nirsevimab are vital for reducing the impact of this respiratory illness.

Keywords:
COVID‐19RSVacute bronchiolitisacute lower respiratory infectioninfant

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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
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Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Public Health

Background:

  • Acute bronchiolitis is a major cause of infant hospitalizations globally.
  • The COVID-19 pandemic impacted bronchiolitis hospitalization rates and disease severity.
  • Understanding post-pandemic trends is crucial for managing infant respiratory illnesses.

Purpose of the Study:

  • To compare the severity of acute bronchiolitis before and after the COVID-19 pandemic.
  • To analyze changes in the epidemiology of viral agents causing bronchiolitis.
  • To assess the impact of the pandemic on infant hospitalizations for bronchiolitis.

Main Methods:

  • Retrospective analysis of medical records for infants under 12 months hospitalized with acute bronchiolitis.
  • Data collected over a 5-year period: 2 years pre-COVID, 1 COVID year, and 2 post-COVID years.
  • Standardized forms used for collecting clinical and laboratory data.

Main Results:

  • Hospital admissions for bronchiolitis decreased during the COVID year but returned to pre-COVID rates post-pandemic.
  • Post-COVID, bronchiolitis cases showed increased severity, longer hospital stays, and higher oxygen therapy needs.
  • A significant surge in Respiratory Syncytial Virus (RSV) infections was observed post-COVID, with RSV-positive patients being younger and more severely ill.

Conclusions:

  • Bronchiolitis severity and RSV prevalence significantly increased following the COVID-19 pandemic.
  • Preventive strategies, including nirsevimab, are essential to mitigate the burden of respiratory infections in infants.
  • Ongoing research and vigilance are necessary to address evolving bronchiolitis challenges.