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Femoro-popliteal bypass versus remote endarterectomy: a propensity matched analysis
Saaya B Shoraan1, Alexander A Gostev2, Olesya S Osipova2
1Department of Vascular and Hybrid Surgery, National Medical Research Center, Ministry for Public Health Care of Russian Federation, Novosibirsk, Russia - shoraans@gmail.ru.
Insights
Femoropopliteal bypass (FPB) and remote endarterectomy (RE) showed comparable outcomes for long femoropopliteal lesions. Great saphenous vein (GSV) bypass and RE demonstrated superior results compared to PTFE bypass for secondary patency and revascularization.
Area of Science:
- Vascular Surgery
- Endovascular Procedures
- Surgical Outcomes Analysis
Background:
- Long femoropopliteal occlusions present a significant challenge in peripheral artery disease treatment.
- Femoropopliteal bypass (FPB) and remote endarterectomy (RE) are surgical options for these complex lesions.
Purpose of the Study:
- To compare the effectiveness of femoropopliteal bypass (FPB) versus remote endarterectomy (RE) for treating long femoropopliteal lesions.
- To evaluate outcomes including primary and secondary patency, and target lesion revascularization.
Main Methods:
- Retrospective analysis of symptomatic patients with femoro-popliteal segment occlusions (>250 mm) from 2014-2020.
- Propensity score matching was used to compare patients undergoing FPB (above the knee) with those undergoing RE.
- Primary endpoints included primary patency (PP), secondary patency (SP), and target lesion revascularization (TLR).
Main Results:
- Three-year primary patency rates were 62% for FPB vs. 53% for RE (P=0.16).
- Secondary patency rates were 84% for FPB vs. 75% for RE (P=0.10).
- Great saphenous vein (GSV) bypass and RE showed statistically significant advantages over PTFE bypass in SP, TLR, and amputation-free survival (AFS).
Conclusions:
- Surgical treatment using autovenous bypass (GSV) or RE demonstrated superior secondary patency, TLR, and AFS compared to PTFE prostheses.
- GSV bypass remains the preferred method for femoropopliteal bypass surgery due to its favorable outcomes.
Background:
The purpose of this study was to compare femoropopliteal bypass (FPB) and remote endarterectomy (RE) for long femoropopliteal lesions.
Methods:
Single center retrospective propensity matching analysis of the symptomatic patients with long occlusion of the femoro-popliteal segment (>250 mm), who underwent femoro-popliteal bypass above the knee or remote endarterectomy from 2014 to 2020. Primary endpoints: primary patency (PP), secondary patency (SP), target lesion revascularization (TLR). Secondary endpoints: MALE, MACE, clinical improvement and survival.
Results:
Four hundred patients were divided into two groups: 200 in the FPB group and 200 in the RE group. As a result of propensity score matching, 110 (FPB) and 109 (RE) patients remained. Three-year primary patency rates were 62% for FPB vs. 53% for RE, P=0.16. Secondary patency rates were 84% for FPB vs. 75% for RE, P=0.10. Freedom from TLR were 61% for FPB vs. 71% for RE P=0.21. Survival and amputation-free survival (AFS) also did not differ (93% vs. 94%, P=0.81 and 87% vs. 92%, P=0.19 respectively). Primary patency of the GSV higher than RE (P=0.00) and PTFE (P=0.00). It was established statistically advantages of RE and great saphenous vein (GSV) bypass over a PTFE bypass in SP (P=0.01 P=0.03), TLR (P=0.02 P=0.00) and AFS (P=0.03 P=0.01).
Conclusions:
Surgical treatment of long femoropopliteal occlusions with an autovenous bypass or remote endarterectomy showed significantly better results in secondary patency, TLR and AFS than the use of PTFE prostheses. GSV remains the gold standard for femoropopliteal bypass surgery.
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