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Updated: Jun 21, 2025
Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans
Published on: November 14, 2016
Research Progress of ARTP Mutagenesis Technology Based on Citespace Visualization Analysis.
Shun Gao1,2, Li Li1,2, Yonggong Wei2
1Liquor Brewing Biotechnology and Application Key Laboratory of Sichuan Province, Sichuan University of Science and Engineering, Yibin, 644000, Sichuan, China.
Atmospheric and room temperature plasma (ARTP) mutagenesis is a rapidly advancing technology for creating large mutation libraries. This study analyzes ARTP research trends, identifying China as the leading country and Jiangnan University as a key institution.
Area of Science:
- Biotechnology
- Genetics
- Environmental Science
Background:
- Atmospheric and room temperature plasma (ARTP) mutagenesis technology offers advantages like simplicity, safety, and high mutation rates.
- Its applications span traditional fields (food, agriculture, medicine) and emerging areas (environmental remediation, bioenergy, microalgae).
Purpose of the Study:
- To analyze the research progress and hotspots of ARTP mutagenesis technology.
- To visualize and understand the global research landscape of ARTP mutagenesis.
Main Methods:
- Bibliometric analysis using the Web of Science Core Collection (WOSCC) database.
- Visualization of keywords and core literature using CiteSpace software.
Main Results:
- China leads in the number of studies on ARTP mutagenesis.
- Jiangnan University is the most prolific institution and has the most published papers.
- Fermentation-related fields, biosynthesis, and molecular-level microbial research are key application areas.
Conclusions:
- ARTP mutagenesis is a significant tool with expanding applications.
- Escherichia coli and Saccharomyces cerevisiae are frequently studied microorganisms in ARTP research.
- The research highlights key contributors and application trends in ARTP mutagenesis.
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