Mind the gap in kidney care: translating what we know into what we do

Valerie A Luyckx1,2,3, Katherine R Tuttle4,5, Dina Abdellatif6

  • 1University of Zurich, Epidemiology, Biostatistics and Prevention Institute, Department of Public and Global Health, Zurich, Switzerland.

PubMed

Insights

Bridging the gap between kidney disease knowledge and practice is crucial. Early diagnosis and treatment, despite existing guidelines, are hindered by numerous barriers, necessitating immediate action.

Area of Science:

  • Nephrology
  • Public Health
  • Translational Medicine

Background:

  • New kidney disease treatments are available but face a 17-year delay in clinical practice.
  • Effective interventions for hypertension and diabetes, key kidney disease risk factors, are underutilized globally.
  • Most individuals with kidney disease remain undiagnosed due to asymptomatic early stages.

Discussion:

  • A significant gap exists between evidence-based kidney disease prevention/management guidelines and actual patient care.
  • Barriers to early diagnosis and treatment span patient, clinician, health system, and societal levels.
  • Delayed or inadequate treatment of kidney disease leads to severe outcomes, including kidney failure and mortality.

Key Insights:

  • Early diagnosis and intervention are critical for preventing severe kidney disease progression and improving patient outcomes.
  • Primary care settings are vital for maximizing opportunities in early kidney disease detection and treatment.
  • Systematic barriers impede the translation of effective kidney disease treatments into widespread clinical practice.

Outlook:

  • Addressing multifactorial barriers is essential for timely implementation of kidney disease treatments.
  • Developing and implementing sustainable solutions is imperative to improve global kidney health.
  • Urgent action is needed to narrow the gap between kidney disease knowledge and clinical application.

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