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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Mind the gap in kidney care: translating what we know into what we do
Valerie A Luyckx1,2,3, Katherine R Tuttle4,5, Dina Abdellatif6
1University of Zurich, Epidemiology, Biostatistics and Prevention Institute, Department of Public and Global Health, Zurich, Switzerland.
Abstract:
Historically, it takes an average of 17 years for new treatments to move from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. Now is the time to narrow the gap between what we know and what we do. Clear guidelines exist for the prevention and management of common risk factors for kidney disease, such as hypertension and diabetes, but only a fraction of people with these conditions are diagnosed worldwide, and even fewer are treated to target. Similarly, the vast majority of people living with kidney disease are unaware of their condition, because it is often silent in the early stages. Even among patients who have been diagnosed, many do not receive appropriate treatment for kidney disease. Considering the serious consequences of kidney disease progression, kidney failure, or death, it is imperative that treatments are initiated early and appropriately. Opportunities to diagnose and treat kidney disease early must be maximized beginning at the primary care level. Many systematic barriers exist, ranging from the patient to the clinician to the health systems to societal factors. To preserve and improve kidney health for everyone everywhere, each of these barriers must be acknowledged so that sustainable solutions are developed and implemented without further delay.
Insights
Bridging the gap between kidney disease knowledge and practice is crucial. Early diagnosis and treatment, despite existing guidelines, are hindered by numerous barriers, necessitating immediate action.
Area of Science:
- Nephrology
- Public Health
- Translational Medicine
Background:
- New kidney disease treatments are available but face a 17-year delay in clinical practice.
- Effective interventions for hypertension and diabetes, key kidney disease risk factors, are underutilized globally.
- Most individuals with kidney disease remain undiagnosed due to asymptomatic early stages.
Discussion:
- A significant gap exists between evidence-based kidney disease prevention/management guidelines and actual patient care.
- Barriers to early diagnosis and treatment span patient, clinician, health system, and societal levels.
- Delayed or inadequate treatment of kidney disease leads to severe outcomes, including kidney failure and mortality.
Key Insights:
- Early diagnosis and intervention are critical for preventing severe kidney disease progression and improving patient outcomes.
- Primary care settings are vital for maximizing opportunities in early kidney disease detection and treatment.
- Systematic barriers impede the translation of effective kidney disease treatments into widespread clinical practice.
Outlook:
- Addressing multifactorial barriers is essential for timely implementation of kidney disease treatments.
- Developing and implementing sustainable solutions is imperative to improve global kidney health.
- Urgent action is needed to narrow the gap between kidney disease knowledge and clinical application.
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