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Longitudinal associations of social jetlag with obesity indicators among adolescents - Shanghai adolescent cohort

  • 0The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China.
Sleep Medicine +

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July 11, 2024

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July 11, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

High social jetlag (SJL) in adolescents is linked to obesity development, particularly in girls. This association is stronger with higher baseline cortisol and progesterone levels.

Area Of Science

  • Adolescent Health
  • Endocrinology
  • Chronobiology

Background

  • Social jetlag (SJL), a mismatch between biological and social sleep timing, is increasingly prevalent among adolescents.
  • Understanding the longitudinal impact of SJL on adolescent health, specifically obesity development, is crucial for public health interventions.

Purpose Of The Study

  • To investigate the long-term association between social jetlag and obesity development in adolescents.
  • To examine sex differences and the modifying roles of cortisol, progesterone, and body composition in this relationship.

Main Methods

  • A 4-year longitudinal study of 609 adolescents (grades 6-9) in Shanghai.
  • Social jetlag assessed via questionnaires; anthropometric measures, fingernail cortisol/progesterone, and body composition analyzed.
  • Latent-class-mixture-modeling identified SJL trajectories; prospective associations with weight/fat gain analyzed by sex and hormone levels.

Main Results

  • High-level SJL trajectories were associated with increased BMI Z-scores, waist-to-height ratios, body fat percentage, and fat-mass index.
  • These associations were significantly stronger in adolescent girls compared to boys.
  • Elevated baseline cortisol and progesterone levels (moderate-to-high) amplified the link between high SJL and obesity markers.

Conclusions

  • High social jetlag in adolescents is a potential risk factor for obesity development.
  • Adolescent girls and those with higher baseline cortisol/progesterone levels are particularly vulnerable to SJL-associated obesity.
  • This highlights the importance of addressing sleep timing discrepancies in adolescent health strategies.

Keywords:

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