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Updated: Jun 21, 2025

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
Published on: March 19, 2019
Breathe and bloom: Gut hypoxia limits C. albicans growth
Animesh A Mishra1, Andrew Y Koh2
1Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Abstract:
Multiple host and microbial factors dictate whether Candida albicans can colonize the mammalian gastrointestinal tract. In this issue of Cell Host & Microbe, Savage et al. demonstrate that restoration of intestinal epithelial hypoxia is sufficient to restore Candida albicans colonization resistance, even when other Candida inhibitory effectors remain depleted.
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