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Aortic root dilation in acromegaly
Yvette Ayewa Yeboah-Kordieh1, Waqar Arif2, David Weisman3
1Internal Medicine, MedStar Union Memorial Hospital, Baltimore, Maryland, USA yvetteeliza93@gmail.com.
BMJ Case Reports
|July 11, 2024
Summary
Persistent high growth hormone (GH) and insulin-like growth factor-1 (IGF-1) can cause aortic root dilation. This case highlights the importance of monitoring and intervention for acromegaly patients with aortic dilation, even below surgical thresholds.
Area of Science:
- Endocrinology
- Cardiology
- Radiology
Background:
- Persistent elevations in growth hormone (GH) and insulin-like growth factor-1 (IGF-1) are associated with cardiovascular complications, notably aortic root dilation.
- Management guidelines for aortic root dilation below surgical thresholds in patients with acromegaly remain undefined, yet timely intervention is crucial.

