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Related Experiment Video

Updated: Jun 21, 2025

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research

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Aortic root dilation in acromegaly.

Yvette Ayewa Yeboah-Kordieh¹, Waqar Arif², David Weisman³

¹Internal Medicine, MedStar Union Memorial Hospital, Baltimore, Maryland, USA yvetteeliza93@gmail.com.

BMJ Case Reports

|July 11, 2024

Summary

This summary is machine-generated.

Persistent high growth hormone (GH) and insulin-like growth factor-1 (IGF-1) can cause aortic root dilation. This case highlights the importance of monitoring and intervention for acromegaly patients with aortic dilation, even below surgical thresholds.

Area of Science:

Endocrinology
Cardiology
Radiology

Background:

Persistent elevations in growth hormone (GH) and insulin-like growth factor-1 (IGF-1) are associated with cardiovascular complications, notably aortic root dilation.

Keywords:

arteries general practice / family medicine pituitary disorders

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Management guidelines for aortic root dilation below surgical thresholds in patients with acromegaly remain undefined, yet timely intervention is crucial.