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Updated: Jun 21, 2025
Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research
Published on: April 26, 2019
Case Report: Post-transplant lymphoproliferative disorder as a serious complication of vascularized composite
Alessandra Zaccardelli1, Fabienne M Lucas2, Ann S LaCasce3
1Department of Medical Education, Tufts University School of Medicine, Boston, MA, United States.
Abstract:
Vascularized composite allotransplantation (VCA) is an emerging field in transplant surgery. Despite overall positive outcomes, VCA confers risk for multiple complications related to the procedure and subsequent immunosuppression. Post-transplant lymphoproliferative disorder (PTLD) is a heterogeneous group of lymphoproliferative disorders occurring after solid organ and hematopoietic stem cell transplant. A patient with PTLD after bilateral upper extremity transplantation is presented as well as a review of all known cases of PTLD after VCA, with a focus on the unique epidemiology, presentation, and treatment in this population.
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