Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Thin-Walled Hollow Shafts01:15

Thin-Walled Hollow Shafts

182
In analyzing a thin-walled hollow shaft subjected to torsional loading, a segment with width dx is isolated for examination. Despite its equilibrium state, this segment faces torsional shearing forces at its ends. These forces are quantitatively described by the product of the longitudinal shearing stress on the segment's minor surface and the area of this surface, leading to the concept of shear flow. This shear flow is consistent throughout the structure, indicating a uniform distribution...
182
Shearing Strain01:20

Shearing Strain

252
The shearing strain represents a cubic element's angular change when subjected to shearing stress. This type of stress can transform a cube into an oblique parallelepiped without influencing normal strains. The cubic element experiences a significant transformation when exposed solely to shearing stress. Its shape alters from a perfect cube into a rhomboid, clearly demonstrating the effect of shearing strain. The degree of this strain is considered positive if it reduces the angle between...
252
Types of Fluids01:27

Types of Fluids

232
Fluids can be classified into Newtonian and non-Newtonian fluids based on their response to shear stress. Newtonian fluids have a linear relationship between shear stress and the shear strain rate, following Newton's law of viscosity. Their viscosity remains constant regardless of the shear rate, making their behavior predictable and easier to analyze. Common examples include water, air, oil, and gasoline.
In contrast, non-Newtonian fluids do not follow Newton's law of viscosity, and...
232
Newtonian Fluid: Problem Solving01:18

Newtonian Fluid: Problem Solving

211
Newtonian fluids exhibit a constant viscosity, meaning their shear stress and shear strain rate are directly proportional. This property ensures a predictable and stable response to applied forces, maintaining a linear relationship between force and flow. Examples include water, air, and light oils, consistently demonstrating this proportional behavior regardless of external conditions.
A velocity gradient forms within the fluid when a Newtonian fluid is placed between two parallel plates, with...
211
Problem Solving on Stress and Strain01:22

Problem Solving on Stress and Strain

726
Stress is a quantity that describes the magnitude of a force that causes deformation, generally defined as internal force per unit area. When forces pull on an object and cause its elongation, like the stretching of an elastic band, it is called tensile stress. When forces cause the compression of an object, it is known as compressive stress. When an object is being squeezed uniformly from all sides, like a submarine in the depths of the ocean, we call this kind of stress bulk stress (or volume...
726

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Viscoelasticity and elastoplasticity in the power law creep and yielding of gels and fibre network materials under stress.

Soft matter·2026
Same author

MultiCell: geometric learning in multicellular development.

Nature methods·2025
Same author

Origin of yield stress and mechanical plasticity in model biological tissues.

Nature communications·2025
Same author

Regulation of chromatin modifications through coordination of nucleus size and epithelial cell morphology heterogeneity.

Communications biology·2025
Same author

Ductile-to-brittle transition and yielding in soft amorphous materials: perspectives and open questions.

Soft matter·2024
Same author

A shape-driven reentrant jamming transition in confluent monolayers of synthetic cell-mimics.

Nature communications·2024
Same journal

Connectivity Structure and Dynamics of Nonlinear Recurrent Neural Networks.

Physical review. X·2026
Same journal

Electric Field of DNA in Solution: Who Is in Charge?

Physical review. X·2025
Same journal

Spontaneous Brain Activity Emerges from Pairwise Interactions in the Larval Zebrafish Brain.

Physical review. X·2025
Same journal

Terahertz-Rate Kerr-Microresonator Optical Clockwork.

Physical review. X·2025
Same journal

Towards the optical second: verifying optical clocks at the SI limit.

Physical review. X·2024
Same journal

Morphological Entanglement in Living Systems.

Physical review. X·2024
See all related articles

Related Experiment Video

Updated: Jun 21, 2025

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix
09:13

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix

Published on: July 10, 2020

3.1K

Discontinuous Shear Thickening in Biological Tissue Rheology.

Michael J Hertaeg1, Suzanne M Fielding1, Dapeng Bi2

  • 1Department of Physics, Durham University, Science Laboratories, South Road, Durham DH1 3LE, United Kingdom.

Physical Review. X
|July 12, 2024
PubMed
Summary
This summary is machine-generated.

This study models 2D confluent tissues to explore how internal cell stresses and external forces interact. It reveals complex rheological behaviors like shear thickening and yielding, offering insights into tissue mechanics.

Keywords:
Biological PhysicsSoft MatterStatistical Physics

More Related Videos

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry
11:19

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry

Published on: September 6, 2016

12.4K
Live Cell Analysis of Shear Stress on Pseudomonas aeruginosa Using an Automated Higher-Throughput Microfluidic System
09:12

Live Cell Analysis of Shear Stress on Pseudomonas aeruginosa Using an Automated Higher-Throughput Microfluidic System

Published on: January 16, 2019

7.5K

Related Experiment Videos

Last Updated: Jun 21, 2025

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix
09:13

Macro-Rheology Characterization of Gill Raker Mucus in the Silver Carp, Hypophthalmichthys molitrix

Published on: July 10, 2020

3.1K
Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry
11:19

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry

Published on: September 6, 2016

12.4K
Live Cell Analysis of Shear Stress on Pseudomonas aeruginosa Using an Automated Higher-Throughput Microfluidic System
09:12

Live Cell Analysis of Shear Stress on Pseudomonas aeruginosa Using an Automated Higher-Throughput Microfluidic System

Published on: January 16, 2019

7.5K

Area of Science:

  • Biophysics
  • Soft Matter Physics
  • Developmental Biology

Background:

  • Embryonic development and adult tissue function depend on cells withstanding mechanical stress and flowing collectively.
  • Tissue mechanics studies have often focused separately on responses to external forces or intrinsic cellular activity.
  • Understanding the interplay between internal and external forces is crucial for tissue development and homeostasis.

Purpose of the Study:

  • To investigate the combined effects of global external deformations and local active stresses from cell motility on 2D confluent tissue mechanics.
  • To elucidate how this interplay dictates emergent mechanical properties of the entire tissue.
  • To explore rheological phenomena near solid-fluid jamming transitions.

Main Methods:

  • Utilized an active vertex model for a 2D confluent tissue.
  • Simulated the interplay between externally applied global deformations and internally generated local active stresses.
  • Analyzed tissue behavior near solid-fluid jamming/unjamming transitions.

Main Results:

  • Observed yielding, shear thinning, continuous shear thickening, and discontinuous shear thickening.
  • Demonstrated how the interplay of internal and external forces governs emergent tissue rheology.
  • Identified a range of fascinating rheological phenomena.

Conclusions:

  • The active vertex model provides a framework for understanding complex tissue rheology.
  • Model predictions align with recently observed nonlinear rheological behaviors in vivo.
  • This work bridges the gap between single-cell active processes and macroscopic tissue mechanics.