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Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
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Longitudinal Changes in a Claims-Based Frailty Proxy Measure Compared to Concurrent Changes in the Fried Frailty
Emilie D Duchesneau1, Dae Hyun Kim2,3, Til Stürmer4,5
1Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Summary
Measuring frailty transitions is challenging. The Faurot frailty index, a claims-based proxy, showed increases mirroring worsening frailty phenotypes in older adults over three years.
Area of Science:
- Gerontology
- Health Services Research
Background:
- Frailty is a dynamic, aging-related syndrome that is difficult to measure.
- The Faurot frailty index is a validated proxy for frailty using Medicare claims data.
- Assessing the consistency of claims-based frailty measures with clinical frailty phenotypes is crucial for accurate monitoring.
Purpose of the Study:
- To evaluate if 3-year changes in the Faurot frailty index align with concurrent changes in the frailty phenotype.
- To determine the utility of Medicare claims data in tracking clinically meaningful frailty progression.
Main Methods:
- Utilized longitudinal data from the National Health and Aging Trends Study (NHATS) linked with Medicare claims (2010-2018).
- Included older adults (66+ years) from 2011 and 2015 NHATS cohorts with continuous Medicare enrollment.
- Analyzed annual changes in claims-based frailty against concurrent transitions in the frailty phenotype over three years.
Main Results:
- At baseline, participants were categorized as robust (32%), prefrail (48%), or frail (19%) by phenotype.
- Individuals whose frailty phenotype worsened from robust to frail showed a significant increase in claims-based frailty (0.09 to 0.25).
- Worsening from prefrail to frail also corresponded with increased claims-based frailty (0.14 to 0.26), though improvements in phenotype did not show corresponding decreases.
Conclusions:
- Worsening of the frailty phenotype over three years was concurrently reflected by increases in the Faurot frailty index.
- Medicare claims data, through the Faurot frailty index, can potentially identify clinically significant worsening of frailty in older adults.
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