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Updated: Jun 21, 2025

15:08
Monitoring Astrocyte Reactivity and Proliferation in Vitro Under Ischemic-Like Conditions
Published on: October 21, 2017
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Activity-induced reactivity of astrocytes impairs cognition
Kirsten Bohmbach1, Christian Henneberger1,2
1Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, Bonn, Germany.
Plos Biology
|July 12, 2024
Abstract:
Glial cells such as astrocytes can modulate neuronal signaling. Astrocytes can also acquire a reactive phenotype that correlates with cognitive impairments in brain diseases. A study in PLOS Biology shows that prolonged activation of astrocytes can trigger both cognitive impairments and a reactive astrocyte phenotype.

