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Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
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Thrifty tissues prefer recycled purines over new-cleotides
David Sokolov1, Lucas B Sullivan1
1Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
Molecular Cell
|July 12, 2024
Abstract
None:
In two recent studies appearing in Cell1 and Cell Metabolism,2 Tran et al. and Wu et al. describe underappreciated nuance in organismal and cellular purine nucleotide salvage pathways and identify purine salvage as a metabolic limitation for tumor growth.
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