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Updated: Jun 21, 2025
One-day Workflow Scheme for Bacterial Pathogen Detection and Antimicrobial Resistance Testing from Blood Cultures
Published on: July 9, 2012
Early detection of bacteremia pathogens with rapid molecular diagnostic tests and evaluation of effect on intensive
Tuba Tatli-Kis1, Suleyman Yildirim2, Can Bicmen3
1Department of Clinical Microbiology and Infectious Diseases, Health Sciences University Izmir Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Gaziler Street. No: 331, Izmir, Yenişehir, Turkey.
Abstract:
İNTRODUCTION: The BioFire FilmArray Blood Culture Identification panel (BCID2), a rapid molecular blood culture identification test based on multiplex nested polymerase chain reaction. The aim of this study was to evaluate clinical outcomes between the period before (pre-BCID2 group) and after (post-BCID2 group) the introduction of the BCID2 panel into our routine practice.
Methods:
The primary endpoint was time to optimal antibiotherapy, and the secondary endpoints were duration of hospital and intensive care unit stay, 7-day, 14-day and 28-day mortality rates after bacteremia.
Results:
The median time from empirical antibiotherapy to optimal antimicrobial therapy was 4560 (IQR;3060-7140) minutes in the pre-BCID2 group and 1715 (IQR;1362- 2776.25) minutes (in the post-BCID2 group (p<0.05).
Conclusion:
Adding the BCID2 panel may improve antibiotic management in critically ill bacteremia patients.
