Large scale production of human fibroblast interferon in multitray battery systems

Several years of experience with the use of Multitray Units (Nunc, Denmark) has shown that this system is an efficient and safe method for the large scale production of human fibroblast Interferon. Further developments of the basic principles have led to the manufacture of a Multitray Unit with a total culture area of 24,000 cm2, the Multitray Battery. The use of Multitrays and Multitray Batteries in large scale interferon production is presented, as well as the development in automation of the handling of large numbers of units.