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Potentially Inappropriate Medication: A Pilot Study in Institutionalized Older Adults
Amanda Andrade1, Tânia Nascimento1,2, Catarina Cabrita1
1Escola Superior de Saúde, Universidade do Algarve (ESSUAlg), Campus de Gambelas, Edifício 1, 8005-139 Faro, Portugal.
Healthcare (Basel, Switzerland)
|July 13, 2024
Summary
Institutionalized elders frequently experience medication-related problems, with over 90% using multiple drugs and over 86% taking potentially inappropriate medications (PIM). Comprehensive medication reviews are vital for this population.
Area of Science:
- Gerontology
- Pharmacology
- Public Health
Background:
- Institutionalized older adults often have complex medication regimens.
- Polypharmacy, drug interactions, and PIM use increase adverse drug event risk.
- Data on medication use in this population are limited.
Purpose of the Study:
- To characterize medication use and PIM in institutionalized elders.
- To assess sociodemographic, clinical, and pharmacotherapeutic profiles.
- To identify medication-related risks in Algarve's ERPI residents.
Main Methods:
- Cross-sectional study of 96 institutionalized elders (mean age 86.6).
- Medication profiles reviewed by trained researchers.
- Potentially Inappropriate Medications identified using the EU(7)-PIM list.
Main Results:
- Over 90% had polypharmacy (average 9.1 medications).
- Approximately 92% experienced potential drug interactions.
- Over 86% used at least one PIM, predominantly CNS drugs.
Conclusions:
- Institutionalized elders face high risks of medication-related problems.
- Comprehensive medication reviews are essential.
- Adapted prescribing practices are needed to optimize care.
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