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Updated: Jun 21, 2025
05:42
Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
Published on: October 25, 2024
1.1K
Real Implication of Fertility-Sparing Surgery for Ovarian Cancer: Reproductive Outcomes
Marta Heras1, Maria Alonso-Espias2, Octavio Arencibia3
1Gynecology Department, Hospital Universitario Santa Cristina, 28009 Madrid, Spain.
Diagnostics (Basel, Switzerland)
|July 13, 2024
Summary
Fertility-sparing management for early-stage ovarian cancer offers good pregnancy success rates with minimal complications. Careful patient selection is crucial for maintaining a positive prognosis in these young women.
Area of Science:
- Gynecologic Oncology
- Reproductive Medicine
- Oncology
Background:
- Assessing the efficacy of fertility-sparing procedures in early-stage ovarian cancer.
- Evaluating pregnancy rates and obstetrical outcomes in young cancer patients.
Purpose of the Study:
- To determine the effectiveness of fertility-sparing management in early-stage ovarian cancer.
- To analyze pregnancy and obstetrical outcomes in patients aged 18-40.
Main Methods:
- Retrospective multicenter study across 55 Spanish hospitals (2010-2019).
- Included patients aged 18-40 with early-stage epithelial (EOC) or non-epithelial (non-EOC) ovarian cancer.
- Collected data on assisted reproductive techniques, pregnancy attempts, and obstetrical outcomes.
Main Results:
- 150 patients included: 70 EOC (46.6%) and 80 non-EOC (53.4%).
- 51 patients (34%) attempted pregnancy, with 42 (28%) achieving term pregnancy.
- 32 spontaneous pregnancies (76.1%) and 10 (23.9%) via in vitro fertilization; only one complication reported.
Conclusions:
- Fertility-sparing management is a viable option for early-stage ovarian cancer, demonstrating good pregnancy rates.
- Strict patient selection criteria are essential for successful outcomes and prognosis.
- Low complication rates support the safety of these procedures.
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