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Updated: Jun 21, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Fetal thymus size in pregnant women with Hashimoto disease
Esin Kasap1, Ceren Saglam2, Raziye Torun2
1Department of Obstetrics and Gynecology, University of Health Sciences Tepecik Training and Research Hospital, İzmir, Türkiye.
Purpose:
This study compared fetal thymic-thoracic ratios and fetal thymus transverse diameter measurements in pregnant women with Hashimoto's thyroiditis (HT) and non-immune hypothyroidism.
Methods:
The study included a total of 141 pregnant women in three groups: 41 with HT, 50 with non-immune hypothyroidism, and 50 healthy individuals. Fetal thymus transverse diameter and thymic-thoracic ratio were compared between these groups.
Results:
The mean fetal thymic-thoracic ratio was greater in pregnant women with HT than in the healthy controls (p = 0.031). Mean fetal thymus transverse diameter showed no statistically significant difference between the groups.
Conclusions:
Maternal HT was associated with an increased fetal thymic-thoracic ratio. More comprehensive studies are needed on this subject.
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