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Biomarkers: how to consolidate them in clinical practice
María Jesús García de Yébenes Prous1, Loreto Carmona Ortells1
1Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain.
Abstract:
An inadequate biomarker validation can affect many patients' diagnosis, treatment, and follow-up. Therefore, special interest should be placed on performing these analyses correctly so that biomarkers can be applicable to patients and evidence of their clinical usefulness can be generated. A methodological work on the concept of biomarkers is presented, as well as the difficulties associated with the methodological approach to their development, validation, and implementation in clinical practice.
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