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Elevated Mood Induced by Subthalamic Nucleus Deep Brain Stimulation: A Video-Recorded Case Report.
Patricia B Coutinho1,2, Kara A Johnson1,2, Andreea L Seritan3,4,5
1Department of Neurology, University of Florida, Gainesville, FL, USA.
Tremor and Other Hyperkinetic Movements (New York, N.Y.)
|July 15, 2024
Summary
Subthalamic nucleus deep brain stimulation (DBS) for Parkinson's disease can cause elevated mood. This case report highlights the connection between mood changes and STN activation, aiding in symptom recognition.
Area of Science:
- Neuromodulation
- Neurosurgery
- Psychiatry
Background:
- Deep brain stimulation (DBS) is a therapeutic option for Parkinson's disease (PD) motor symptoms.
- Subthalamic nucleus (STN) DBS may lead to psychiatric side effects, such as mood elevation.
Observation:
- A case of a 73-year-old male patient with bilateral STN DBS experiencing stimulation-induced elevated mood is presented.
- Mood alterations were correlated with increased activation in the ventromedial region of the left STN.
Findings:
- The study illustrates a specific instance of elevated mood induced by STN DBS.
- A link between specific STN activation patterns and mood changes was observed.
Implications:
- This case report aims to improve early recognition of mood elevation as a potential side effect of STN DBS.
- Enhanced awareness among healthcare professionals regarding this adverse effect is crucial for accurate diagnosis and management.
