Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

73
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
73
Schizophrenia01:17

Schizophrenia

74
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
74
Prosopagnosia01:24

Prosopagnosia

154
Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
154
Visual Agnosia01:12

Visual Agnosia

188
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
188
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

53
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
53
Somatosensation01:33

Somatosensation

36.5K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shared and specific associations of amygdala nuclei volumes with PTSD symptom domains and childhood trauma: An ENIGMA-PGC PTSD mega-analysis.

Molecular psychiatry·2026
Same author

Reading speed, visual deficits, and cerebral white matter integrity in veterans with and without mild traumatic brain injury.

Frontiers in neuroscience·2026
Same author

Largely Typical Neural Activation During Monetary Reward Receipt in People With Psychosis-Spectrum Disorders and First-Degree Relatives.

Schizophrenia bulletin·2026
Same author

Frame-wise multi-echo distortion correction for superior functional MRI.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

Anxiety sensitivity and intolerance of uncertainty track distinct neurobehavioral dimensions of avoidance in anxiety-related disorders.

Molecular psychiatry·2026
Same author

White matter microstructure in relatives of people with schizophrenia or bipolar disorder: an ENIGMA meta-analysis.

Molecular psychiatry·2026

Related Experiment Video

Updated: Jun 21, 2025

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior
09:49

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior

Published on: April 16, 2014

25.2K

Impaired contour object perception in psychosis.

Rohit S Kamath1, Kimberly B Weldon2,1, Hannah R Moser1

  • 1Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, USA.

Medrxiv : the Preprint Server for Health Sciences
|July 15, 2024
PubMed
Summary
This summary is machine-generated.

People with psychotic psychopathology exhibit impaired contour integration, a visual processing deficit. This difficulty in perceiving unified lines is linked to cognitive dysfunction and abnormal brain connectivity, particularly in schizophrenia.

More Related Videos

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

6.6K
Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

Published on: June 3, 2013

17.3K

Related Experiment Videos

Last Updated: Jun 21, 2025

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior
09:49

Methods to Explore the Influence of Top-down Visual Processes on Motor Behavior

Published on: April 16, 2014

25.2K
Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

6.6K
Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues

Published on: June 3, 2013

17.3K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Psychiatry

Background:

  • Contour integration, the ability to perceive unified lines from disparate elements, is known to be impaired in schizophrenia.
  • Emerging evidence suggests this deficit may be linked to broader psychotic symptoms rather than specific diagnoses.

Purpose of the Study:

  • To investigate contour integration deficits in a transdiagnostic sample of individuals with psychotic psychopathology (PwPP).
  • To explore the neural underpinnings of these deficits using functional MRI and connectivity analyses.

Main Methods:

  • A psychophysical behavioral task was used to quantify contour discrimination performance in PwPP, healthy controls, and relatives of PwPP.
  • Ultra-high field (7T) functional MRI measured brain activity and functional connectivity during an analogous contour perception task.

Main Results:

  • PwPP demonstrated significantly impaired contour discrimination compared to controls and their relatives.
  • Individuals with schizophrenia performed worse than those with bipolar disorder on the task.
  • PwPP showed heightened activity in the lateral occipital cortex and abnormal visual functional connectivity, especially when distinguishing targets from distractors.

Conclusions:

  • Contour integration is impaired across psychotic psychopathology, with particular deficits observed in schizophrenia.
  • These visual processing impairments are associated with cognitive dysfunction and aberrant functional connectivity within visual brain networks.
  • A failure to effectively suppress background noise may contribute to the observed contour processing difficulties in PwPP.