Related Experiment Video
Updated: Jun 21, 2026
12:37
Modeling Colitis-Associated Cancer with Azoxymethane AOM and Dextran Sulfate Sodium DSS
Published on: September 11, 2012
46.9K
Tubular Adenoma Arising Within a Rectosigmoid Xanthoma: A Case Report
Kaley Coffey1, Heather L Mateja2, William Bowers2
1General Surgery, Trumbull Regional Medical Center, Warren, USA.
Cureus
|July 15, 2024
Summary
Colonic xanthomas are rare, especially with tubular adenomas in one polyp. This case highlights the need for metabolic screening and increased colon surveillance to prevent future growths.
Area of Science:
- Gastroenterology
- Pathology
- Oncology
Background:
- Colonic xanthomas are uncommon findings.
- Their coexistence with tubular adenomas in a single polyp is particularly rare.
- The pathophysiology and implications for patient outcomes require further investigation.
Observation:
- A patient presented with a rectosigmoid polyp during routine screening colonoscopy.
- Histopathology confirmed the polyp to be a xanthoma with tubular adenoma features.
Findings:
- The polyp exhibited characteristics of both a colonic xanthoma and a tubular adenoma.
- Malignant transformation risk is not considered higher than for tubular adenoma alone.
Implications:
- Metabolic derangements should be investigated in patients with colonic xanthomas.
- Increased colonic surveillance is recommended to monitor for further xanthoma or adenocarcinoma development.
- Understanding xanthoma pathophysiology may offer insights into colonic polyp formation and patient management.
