Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Urinary Bladder

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...

Ureters

Ureters

The ureters are retroperitoneal tubes located on either side of the vertebral column. They are responsible for transporting urine from each kidney to the urinary bladder. These tubes have thick walls and are approximately 25-30 cm long. Their diameter is around 10 mm at the renal pelvis, gradually narrowing to 1 mm as the ureter obliquely enters the posterior bladder wall through the ureteric orifices. The shape of these orifices is slit-like, which helps to prevent urine backflow toward the...

Nephrons

Nephrons

The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pleomorphic Leiomyosarcoma of the Jejunoileal Mesentery: A Histopathological Case Report.

Clinical case reports·2026

Same author

Renal-Type Clear Cell Carcinoma of the Prostate: A Histopathological Case Report of a Rare and Underrecognized Variant.

Reports (MDPI)·2026

Same author

High-Grade Urothelial Carcinoma with Clear-Cell (Glycogen-Rich) Features and Divergent Trophoblastic Differentiation: A Histopathological Case Report.

Reports (MDPI)·2026

Same author

A Case Report of Discoid Lupus Erythematosus Mimicking Skin Infection.

Reports (MDPI)·2026

Same author

When Tears Signal Vasculitis: Bilateral Dacryoadenitis as the Initial Manifestation of Granulomatosis with Polyangiitis-Case Report.

Reports (MDPI)·2026

Same author

Idiopathic Penile Calcinosis Cutis: A Histopathological Case Report.

Reports (MDPI)·2025

Search research articles

Related Experiment Video

Updated: Jun 21, 2025

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Published on: May 29, 2015

Urinary Bladder Nephrogenic Adenoma: A Histopathological Case Report.

Hristo Popov¹, Andreya Kirilova¹, Kristina Naydenova¹

¹General and Clinical Pathology, Forensic Medicine and Deontology, Medical University of Varna, Varna, BGR.

|July 15, 2024

Summary

Nephrogenic adenomas, benign urinary tract lesions, can occur after urothelial carcinoma treatment. This case highlights their development in a patient with a history of bladder cancer, emphasizing diagnostic considerations.

Keywords:

benign lesions nephrogenic adenoma pathology urinary bladder urology

More Related Videos

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

Published on: January 12, 2017

Related Experiment Videos

Last Updated: Jun 21, 2025

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Published on: May 29, 2015

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

Published on: January 12, 2017

Area of Science:

Uropathology
Oncology
Nephrology

Background:

Nephrogenic adenomas are benign urinary tract lesions with unclear origins.
They commonly affect adult males and are associated with prior urinary tract injury, infection, or malignancy.
Renal transplant recipients are also a subset of affected individuals.

Observation:

A male patient in his seventies, previously treated for low-grade, non-invasive urothelial carcinoma, presented with dysuria.
Bladder endoscopy revealed a ureteral stricture and two small exophytic lesions near the prior cancer site.
Histological examination showed complex papillary architecture and cystic spaces lined by monomorphous epithelial cells.

Findings:

The histological features, including papillary architecture and specific cellular morphology, led to the diagnosis of nephrogenic adenoma.
The lesions were located adjacent to the site of previous urothelial carcinoma treatment.
The patient had remained disease-free from urothelial carcinoma for seven years prior to this presentation.

Implications:

This case underscores the importance of considering nephrogenic adenoma in the differential diagnosis of urinary tract lesions, especially in patients with a history of urothelial carcinoma.
Understanding the association between prior urinary tract interventions and nephrogenic adenoma development is crucial for accurate diagnosis and patient management.
Further research into the etiopathogenesis of nephrogenic adenoma may improve diagnostic accuracy and treatment strategies.