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Mouse Kidney Transplantation: Models of Allograft Rejection

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Published on: October 11, 2014

Enhancing Success in the ABO-Incompatible Kidney Transplantation: A Case Report.

D S Rana¹, A K Bhalla¹, Ashwani Gupta¹

¹Nephrology, Sir Ganga Ram Hospital, New Delhi, IND.

|July 15, 2024

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ABO incompatible kidney transplants can be successful using immunoadsorption (IA) to lower antibody titers. This case report shows two IA columns effectively reduced antibodies, enabling a successful kidney transplant.

Area of Science:

Nephrology
Immunology
Transplantation Science

Background:

Kidney transplantation is the optimal treatment for end-stage renal disease (ESRD).
ABO incompatible (ABOi) kidney transplantation (KT) faces challenges due to high isoagglutinin titers, increasing rejection risk.
Desensitization strategies, including immunoadsorption (IA), are crucial for overcoming ABOi barriers.

Keywords:

abo incompatible kidney transplant antibody titer desensitization immunoadsorption column plasmapheresis

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