Related Experiment Video
Updated: Jun 21, 2025
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Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction
Published on: March 7, 2013
36.2K
[Liver transplantation program at the Burnasyan Federal Biophysical Center: experience in 500 procedures]
S E Voskanyan1, A I Sushkov1, A I Artemiev1
1Burnasyan Federal Biophysical Center, Moscow, Russia.
Khirurgiia
|July 15, 2024
Summary
Liver transplantation is effective for liver diseases. Living donors improve outcomes and reduce mortality compared to deceased donors, enhancing patient survival rates significantly.
Area of Science:
- Hepatology and Transplant Surgery
- Clinical Outcomes Research
- Organ Transplantation
Context:
- Analysis of 500 adult liver transplantations over 12 years (May 2010 - April 2023).
- Inclusion of 483 recipients and 438 candidates from a local registry.
- Data collection up to June 1, 2023, with statistical analysis using Statistica 12 and Jamovi.
Purpose:
- To analyze the features and outcomes of adult liver transplantations.
- To compare outcomes between living-related and deceased donors.
- To assess the effectiveness of liver transplantation for various liver diseases.
Summary:
- 198 liver transplantations performed out of 438 candidates; 1- and 3-year survival rates were 81% and 50%.
- Living-related donors (73%) showed superior outcomes: 1-, 5-, and 7-year survival rates of 89%, 84%, and 80% respectively.
- Deceased donors (27%) resulted in 1-, 5-, and 7-year survival rates of 81%, 66%, and 58%.
Impact:
- Liver transplantation is highly effective for diffuse and focal liver diseases.
- Living donors significantly enhance transplant availability and patient outcomes.
- Living donor transplants reduce recipient mortality by over 20% at 5 years compared to deceased donor transplants.
