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[Association between previous appendectomy and cognitive impairment in adults: a case-control study]
P Castillo Silva1, J Caballero-Alvarado1,2, A Reyes-Vega3
1Antenor Orrego Private University, Trujillo, Peru.
Past appendectomy may increase the risk of cognitive impairment in adults aged 50-70. This study found a significant association between appendectomy and cognitive decline, suggesting a potential risk factor.
Area of Science:
- Neurology
- Epidemiology
- Surgical Outcomes
Context:
- Cognitive impairment affects adults aged 50-70.
- Appendectomy is a common surgical procedure.
- Understanding risk factors for cognitive decline is crucial.
Purpose:
- To investigate the association between appendectomy and cognitive impairment in adults aged 50-70.
- To identify potential surgical risk factors for cognitive decline.
Summary:
- A case-control study of 270 adults (90 with cognitive impairment, 180 controls) aged 50-70 was conducted.
- Appendectomy was significantly associated with cognitive impairment (OR 12.91), alongside cholecystectomy and other surgeries.
- Age, BMI, hypertension, diabetes, and smoking also showed associations with cognitive impairment.
Impact:
- Appendectomy may be a significant risk factor for cognitive impairment.
- Findings highlight the need for further research into the link between surgical history and cognitive health.
- This research could inform preventative strategies for cognitive decline.
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