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Particle arc therapy: Status and potential.

Stewart Mein1, Sophie Wuyckens2, Xiaoqiang Li3

  • 1Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA; Heidelberg Ion-Beam Therapy Center (HIT), Heidelberg, Germany; Division of Molecular and Translational Radiation Oncology, National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany; Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
|July 15, 2024
PubMed
Summary
This summary is machine-generated.

Particle arc therapy, using charged particle beams like protons and carbon ions, is gaining clinical interest. This report outlines the physics, radiobiology, and clinical path for its future implementation.

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Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Particle Therapy

Background:

  • Growing interest in arc delivery techniques for charged particle beams (protons, carbon ions).
  • Need for a clear path towards clinical implementation of particle arc therapy.
  • Importance of interdisciplinary collaboration for advancing novel radiation techniques.

Purpose of the Study:

  • Report perspectives from the European Society for Radiotherapy and Oncology (ESTRO) 2022 physics workshop on particle arc therapy.
  • Provide an outlook and vision for clinically deliverable proton, carbon, and other ion arc treatments.
  • Facilitate community understanding of the physics, radiobiology, and clinical principles of particle arc therapy.

Main Methods:

  • Consolidation of insights from the ESTRO 2022 physics workshop.
  • Collaborative effort involving industry, academia, and clinical research and development.
  • Structured presentation of information across treatment planning, delivery, and clinical outlook.

Main Results:

  • Presentation of the current scientific landscape and future outlook for particle arc therapy.
  • Identification of key areas for development in treatment planning and delivery.
  • Discussion of the clinical potential and considerations for ion beam arc therapy.

Conclusions:

  • Particle arc therapy represents a promising advancement in radiation oncology.
  • Continued collaboration is essential for overcoming technical and clinical challenges.
  • This work provides a foundational overview to guide future research and development in the field.