Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

Chronic Obstructive Pulmonary Disease-V: Management

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Transcriptome analysis of methyl jasmonate-elicited Panax ginseng adventitious roots to discover putative ginsenoside biosynthesis and transport genes.

International journal of molecular sciences·2015

Same author

Research on return visit and investigation of the relapse rate of children allergic purpura after treatment.

Pakistan journal of pharmaceutical sciences·2015

Same author

FASCIATED EAR4 encodes a bZIP transcription factor that regulates shoot meristem size in maize.

The Plant cell·2015

Same author

A maize glutaredoxin gene, abphyl2, regulates shoot meristem size and phyllotaxy.

The Plant cell·2015

Same author

[Tumor microenvironment--the critical element of tumor metastasis].

Zhongguo fei ai za zhi = Chinese journal of lung cancer·2015

Same author

Magnetic microbubble-mediated ultrasound-MRI registration based on robust optical flow model.

Biomedical engineering online·2015

Search research articles

Related Experiment Video

Updated: Jun 21, 2025

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy

Published on: February 21, 2025

Risk Factors of Sarcopenia in COPD Patients: A Meta-Analysis.

Jingru Zhou¹, Yanjun Liu², Fang Yang¹

¹Department of Nursing, Deyang People's Hospital, Deyang, Sichuan, 618200, People's Republic of China.

International Journal of Chronic Obstructive Pulmonary Disease

|July 16, 2024

Summary

Sarcopenia is more common in COPD patients and linked to age, BMI, smoking, diabetes, and qi deficiency. Early screening and prevention information are crucial for high-risk individuals.

Keywords:

chronic obstructive pulmonary disease meta-analysis prevalence risk factors sarcopenia

More Related Videos

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

Related Experiment Videos

Last Updated: Jun 21, 2025

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy

The Creation of a Rat Model for Osteosarcopenia via Ovariectomy

Published on: February 21, 2025

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

Area of Science:

Pulmonary Medicine
Geriatrics
Nutritional Science

Background:

Sarcopenia, characterized by age-related skeletal muscle mass reduction, is prevalent in COPD patients.
COPD patients exhibit double the incidence of sarcopenia compared to non-COPD individuals, indicating a poorer prognosis.

Purpose of the Study:

To investigate the key factors influencing the development of sarcopenia in patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD).

Main Methods:

A systematic review of studies published up to November 2023 from major databases including PubMed, Embase, and Web of Science.
Data extraction was performed independently by two reviewers from 17 selected articles, encompassing 5408 patients aged 18 and above.

Main Results:

Significant factors associated with sarcopenia in COPD patients include advanced age (OR=1.083), low Albumin (ALB) (OR=0.752), low Body Mass Index (BMI) (OR=0.701), smoking (OR=1.859), and diabetes (OR=1.361).
Traditional Chinese Medicine concepts like 'qi deficiency' (OR=9.883) and advanced COPD stages (GOLD C: OR=2.232, GOLD D: OR=2.195) were also identified as significant contributing factors.

Conclusions:

Sarcopenia is highly prevalent in COPD patients, influenced by a combination of demographic, clinical, and disease-specific factors.
Healthcare providers should prioritize early sarcopenia screening in high-risk COPD populations and disseminate relevant preventive strategies.