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Updated: Jun 21, 2025

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs
Published on: February 18, 2022
How to diagnose heart failure with preserved ejection fraction.
Sabina Istratoaie1,2, Luna Gargani3, Bogdan A Popescu4
1Cardiology, University of Rennes, CHU Rennes, Inserm, LTSI-UMR 1099, 2 Rue Henri le Guilloux, F-35000 Rennes, France.
Diagnosing heart failure with preserved ejection fraction (HFpEF) is challenging due to varied symptoms. This review assesses diagnostic methods, emphasizing echocardiography for HFpEF phenotyping and personalized treatment.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- Heart failure with preserved ejection fraction (HFpEF) is a growing global health concern.
- Current management trends focus on early diagnosis and tailored treatments based on patient phenotypes.
- Diagnosing HFpEF is complex due to a lack of universal criteria and significant patient heterogeneity.
Purpose of the Study:
- To comprehensively review the diagnostic workup for HFpEF.
- To emphasize the critical role of echocardiography in identifying distinct HFpEF phenotypes.
Main Methods:
- Literature review of diagnostic strategies for HFpEF.
- Focus on the application of echocardiography in HFpEF phenotyping.
Main Results:
- Echocardiography is instrumental in differentiating HFpEF phenotypes.
- Diagnostic challenges stem from patient variability and non-standardized criteria.
Conclusions:
- Accurate HFpEF diagnosis requires a thorough evaluation, integrating various diagnostic tools.
- Phenotype-specific assessment, particularly via echocardiography, is key for effective HFpEF management.
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