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Updated: Jun 21, 2025
Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
American Society of Transplant Surgeons Normothermic Regional Perfusion Standards: Ethical, Legal, and Operational
Anji E Wall1, Shaheed Merani2, Jason Batten3
1Division of Abdominal Transplantation, Baylor University Medical Center, Dallas, TX.
Background:
The American Society of Transplant Surgeons convened a multidisciplinary working group to address operational, ethical, and legal considerations surrounding normothermic regional perfusion (NRP) procurement.
Methods:
The working group, comprising members from American Society of Transplant Surgeons and AST across various disciplines including transplant surgery, hepatology, critical care, and bioethics, collaborated to formulate recommendations and guidance for NRP procurement.
Results:
The following topics were identified by the group as essential standards that need to be addressed for ethical, legal, and operational conformance: terminology; conceptualization of death in the context of NRP; and communication, logistics, and training and competency.
Conclusions:
Fourteen recommendations that support the ethical and legal acceptability of NRP in the United States and set expectations for the conduct of NRP procedures are provided.
