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Indwelling blood compatible chemical sensors
The Surgical Clinics of North America
|August 1, 1985
Summary
Emerging catheter-tip chemical probes, using fiberoptic or semiconductor technology, offer potential for improved surgical monitoring. Further development is needed to overcome challenges like stability and fouling for clinical use.
Area of Science:
- Surgical Technology
- Biomedical Engineering
- Chemical Sensing
Background:
- Technological advancements are crucial for surgical progress.
- Catheter-tip chemical probes represent an emerging technology with potential clinical applications.
Purpose of the Study:
- To review the development and potential of catheter-tip chemical probes for surgical monitoring.
- To compare fiberoptic-based and semiconductor-based probe technologies.
Main Methods:
- Review of laboratory formulations and limited clinical experience with prototype probes.
- Analysis of reported advantages and disadvantages of fiberoptic and semiconductor probe types.
Main Results:
- Fiberoptic probes offer advantages like no electrical interference but suffer from sensitivity and stability issues.
- Semiconductor probes allow multi-species detection and on-chip processing but require reference electrodes and face in situ instability.
Conclusions:
- Both probe types require further development to address fouling and thromboembolism risks.
- Industrial development suggests these probes may soon become clinical realities.