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Related Experiment Video

Updated: May 2, 2026

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function

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Published on: December 8, 2010

Fluorescein Angiogram Causing Cutaneous Venous Staining: A Rare Self-Resolving Phenomenon.

Zachary George Angus^1,2, Daini Ong¹, Sanjeewa S Wickremasinghe¹

¹Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, VIC, Australia.

Case Reports in Ophthalmology

|July 17, 2024

Summary

This summary is machine-generated.

Cutaneous fluorescein staining along arm veins is a rare side effect of fluorescein angiography (FA). This temporary staining, observed in two patients, resolved naturally without intervention.

Keywords:

Adverse effect Fluorescein angiography Retina Skin Staining

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Area of Science:

Ophthalmology
Medical Imaging

Background:

Fluorescein angiography (FA) is a key diagnostic tool for retinal and choroidal diseases.
While generally safe, FA can cause mild adverse effects.
Cutaneous venous staining is a rarely reported complication of FA.

Observation:

Two cases of cutaneous fluorescein staining following FA are presented.
Case 1: A 90-year-old female with AMD experienced staining ascending forearm veins.
Case 2: A 50-year-old male with diabetic macular edema experienced staining descending forearm veins.

Findings:

Both patients developed temporary staining of superficial forearm veins post-FA.
The staining was localized around the venous access site.
The condition was self-limiting and resolved within days.

Implications:

Cutaneous fluorescein staining is a rare but benign adverse event.
Conservative management is sufficient for this complication.
Awareness of this rare side effect is important for clinicians performing FA.