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Polypoid Large Intestinal Involvement of Metastatic Castrate-Resistant Prostate Cancer: A Case Report.

Sathya Narayanan1,2, Sapir Dvuchbabny2, Arteen Arzivian1,2

  • 1Macquarie University Hospital, Sydney, NSW, Australia.

Case Reports in Oncology
|July 17, 2024
PubMed
Summary
This summary is machine-generated.

Prostate cancer rarely spreads to the gastrointestinal tract. This case highlights metastatic prostate cancer presenting as polyps in both the small and large intestines.

Keywords:
Castrate-resistant prostate cancerGastrointestinal bleedingGastrointestinal metastasisLarge intestinal polyps

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Area of Science:

  • Oncology
  • Gastroenterology
  • Pathology

Background:

  • Prostate cancer commonly metastasizes to bone and lymph nodes.
  • Gastrointestinal metastasis from prostate cancer is rare, with limited reports of large intestinal involvement.
  • Concomitant small and large intestinal metastasis from prostate cancer has not been previously documented.

Observation:

  • A 69-year-old male with metastatic castrate-resistant prostate cancer developed gastrointestinal symptoms.
  • Extensive investigation revealed small and large intestinal polyps.
  • These polyps were confirmed to represent metastatic prostate cancer.

Findings:

  • The case presents the first documented instance of simultaneous small and large intestinal metastasis from prostate cancer.
  • Metastatic prostate cancer can manifest as seemingly unremarkable polyps during endoscopic evaluation.
  • Gastrointestinal symptomatology in cancer patients warrants a broad differential diagnosis.

Implications:

  • This case underscores the necessity of considering metastatic disease in the differential diagnosis of gastrointestinal polyps.
  • Endoscopic evaluation is crucial for identifying metastatic lesions, even when polyps appear benign.
  • Maintaining a high index of suspicion and thorough investigation are vital for accurate diagnosis and management of rare metastatic patterns.