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Autoimmunity and pregnancy.

A El-Roeiy, Y Shoenfeld

    American Journal of Reproductive Immunology and Microbiology : AJRIM
    |September 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Pregnancy

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    Area of Science:

    • Immunology
    • Obstetrics
    • Reproductive Medicine

    Background:

    • The impact of pregnancy on autoimmune diseases is debated, with varied effects observed.
    • Some cases show no change, while others experience disease flares, particularly postpartum.

    Purpose of the Study:

    • To explore the complex relationship between pregnancy and autoimmune conditions.
    • To highlight the risks of disease transfer to the fetus and the need for monitoring.

    Main Methods:

    • Review of existing literature on pregnancy and autoimmunity.
    • Clinical and immunological observation of mother-infant dyads.

    Main Results:

    • Pregnancy's effect on autoimmunity is inconsistent; some women experience no change, others have flares.
    • Autoimmune diseases can transfer passively to the fetus during pregnancy.

    Conclusions:

    • Understanding the pathogenesis and therapy of autoimmune diseases is crucial.
    • Close clinical and immunological monitoring of mother-infant pairs is essential during and after pregnancy.