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Updated: Jun 20, 2025

Knee Arthrocentesis in Adults
Published on: February 25, 2022
Venous thromboembolism After Knee Arthroscopy: Incidence, Risk Factors, Prophylaxis, and Management
Colby C Wollenman1, Charles L Cox, Jonathan G Schoenecker
1From the Department of Orthopaedics, Vanderbilt University Medical Center, Nashville, TN (Wollenman, Cox, Schoenecker, and Wright), the Department of Pathology, Microbiology, and Immunology, the Department of Pediatrics, the Center for Bone Biology, and the Department of Pharmacology, Vanderbilt University, Nashville, TN (Schoenecker).
Abstract:
Venous thromboembolism (VTE), comprising pulmonary embolism and deep vein thrombosis, is one of the most common complications after knee arthroscopy. Sequelae of VTE include VTE recurrence, postthrombotic syndrome, and potential for loss of limb or life. Given the increasing volume of knee arthroscopy procedures worldwide and the considerable morbidity and mortality associated with VTE, it is important to prevent, diagnose, and treat VTEs efficiently and effectively. Risk factors such as history of VTE, family history of VTE, genetic coagulopathy, oral contraceptive use, cancer history, and old age increase the risk of postoperative VTE and warrant consideration of prophylaxis. Diagnosis and treatment should be initiated rapidly in the setting of concerning symptoms and positive imaging diagnosis, respectively. The purpose of this review was to provide a framework to individualized VTE risk, weigh prophylaxis options, expedite diagnostic pathways, and implement outpatient treatment algorithms.
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