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Published on: October 24, 2019
Normative longitudinal EEG recordings during sleep stage II in the first year of age
Thalía Harmony1, Gloria Otero-Ojeda2, Eduardo Aubert-Vázquez3
1Neurodevelopment Research Unit at the Instituto de Neurobiología, Universidad Nacional Autónoma de México; Juriquilla, Querétaro, CP.76230, México. thaliaharmony79@gmail.com.
Insights
This study presents the first dataset of normal infant electroencephalogram (EEG) recordings during the first year of life. These findings provide a baseline for understanding typical brain function in developing infants.
Area of Science:
- Neuroscience
- Pediatric Neurology
- Clinical Electrophysiology
Background:
- The electroencephalogram (EEG) is crucial for assessing brain function.
- Establishing normative EEG data in infants is essential for diagnosing neurological disorders.
- A gap exists in readily available, comprehensive EEG datasets for healthy infants in their first year.
Purpose of the Study:
- To characterize the electroencephalogram (EEG) of healthy, full-term infants.
- To create a foundational dataset of infant EEG for quantitative analysis.
- To provide a reference for future research on infant neurodevelopment and disorders.
Main Methods:
- Collected referential EEG data from 103 healthy infants (15 days to 12.5 months) in Mexico during physiological sleep.
- Utilized linked earlobes as reference, with amplifier gain at 10,000, bandwidth 0.3-30 Hz, and sample rate of 200 Hz.
- Segmented EEG recordings into 2.56-second windows for quantitative analysis.
Main Results:
- Successfully acquired EEG data from a cohort of healthy infants within the first year of life.
- Detailed the technical parameters used for recording and processing the EEG data.
- Established a novel dataset representing normal infant brain activity during early development.
Conclusions:
- This work provides the first known dataset of normal infant EEG recordings for the first year of age.
- The characterized EEG data serves as a valuable normative reference.
- This dataset will aid in the identification of neurodevelopmental abnormalities in infants.
Abstract:
The electroencephalogram (EEG) is a fundamental diagnostic procedure that explores brain function. This manuscript describes the characteristics of a sample of healthy at-term infants. One hundred and three (103) infants from Mexico between 15 days and 12.5 months of age were recorded during physiological sleep. Referential EEG recordings were obtained using linked ear lobes as reference. The amplifier gain was 10,000, the bandwidth was set between 0.3 and 30 Hz, and the sample rate was 200 Hz. Sample windows of 2.56 s were marked for later quantitative analysis. To our knowledge, this is the first dataset of normal infants during the first year of age.
